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. Author manuscript; available in PMC: 2010 Dec 28.
Published in final edited form as: Angew Chem Int Ed Engl. 2008;47(40):7764–7767. doi: 10.1002/anie.200802502

Figure 4.

Figure 4

Protease activation of intein mediated antimicrobial activity. Growth of E. coli incubated with constructs 5 and 6 at 30 μM in the presence and absence of Factor Xa protease. Magainin (MA) and the constitutively active wild type intein (9 + 6) at 30 μM are also shown as positive controls. Bacterial growth (OD650 after 18 h incubation) of each sample relative to a culture control is shown, errors = s.d. (n=3). Inset) Scheme of the DnaE mediated splicing of magainin.