Figure 1.

Viability of bone marrow-derived mesenchymal stromal cells (BMSCs) was decreased by caffeine. BMSCs were treated with different concentrations of caffeine (0, 0.1 and 1 mM) for 48 h and growth assessed by thymidine incorporation (shown as CPM per well). Data show that cell viability was decreased in a concentration-dependent manner. Bars represent the mean ± standard deviation (n = 9). Comparisons between groups were performed using anova. *P < 0.05, significantly different from the control group. CPM, counts per minute.