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. 2010 Dec;161(7):1616–1627. doi: 10.1111/j.1476-5381.2010.00995.x

Figure 5.

Figure 5

Effect of MEN16132 and dexamethasone on LPS-induced knee joint incapacitation. Rats received intra-articularly in the right knee, anti-inflammatory drugs, alone or in combination at the doses indicated, 30 min before injection of saline (control group) or lipopolysaccharide (LPS) (10 µg, 25 µL). Knee joint incapacitation was measured 6 h later. Dotted lines indicate the control value (upper) and the response after LPS treatment (lower). Data are expressed as the mean ± SEM of 6–12 experiments. *P < 0.05 and °P < 0.05, significantly different from the LPS-treated group and control group respectively (one-way anova followed by Dunnett's post-test).