Figure 1.

Uptake of 18 µM [¹⁴C]Gly-Sar in Madin–Darby canine kidney cells (MDCK)/human proton-coupled peptide transporter (hPEPT1) cell monolayers in presence or absence of 0.5 mM acetylsalicylic acid (ASA), etodolac, ibuprofen, naproxen, paracetamol, piroxicam or 20 mM Gly-Pro. The uptake was measured for 5 min with an extracellular pH of 6.0. Data represent mean ± SEM of six cell monolayers. *P < 0.05 and **P < 0.01, analysed by one-way anova followed by Dunnet's post-test (the control column used as control).