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Uptake of 0.1 µM [3H]ibuprofen in Caco-2 cells in 24-well plates in the presence or absence of 1 mM racaemic ibuprofen. Uptake was measured for 5 min using a 2-[N-morpholino]ethanesulfonic acid buffer with a pH of 6.0. Results mean ± SEM of 3 individual cell monolayers in three passages. Statistical analysis was performed using an unpaired Student's t-test, ***P < 0.001.
