Figure 3.

Leucine kinetics in type 1 diabetic adolescent girls consuming a basal diet or a diet supplemented with L-leucine. Protein synthesis, protein degradation, leucine oxidation, and protein balance were calculated from the enrichment of plasma [¹³C]KIC, ¹³CO₂, and CO₂ production as described in Materials and Methods. The data are expressed as μmoles of leucine/kg body weight/h during consumption of the basal diet (19% of calories from fat, 57% of calories from carbohydrate, and 22% from protein) or the basal diet with supplemental L-leucine (total leucine content of 4 times the basal diet). Differences between the study day with the basal diet and the study day with the basal diet supplemented with L-leucine were statistically significant, ∗P < .001.