Table 1.
Group distribution.
| Damage type | Strain | Observation interval | Observation time | Effluent | Liver tissue |
|---|---|---|---|---|---|
| CI | Lewis (n = 6) | 1 h | 24 h | HMGB1; MIF | Histology |
| M+CI | Lewis (n = 6) | 1 h | 24 h | AST; ALT | HMGB1 IHC |
| WI | Lewis (n = 6) | 0,5 h | 6 h | ||
| M+CI | Lewis (n = 6) | 0,5 h | 6 h | ||
| CI | BN (n = 6) | 1 h | 24 h |
CI, cold ischemia; WI, warm ischemia; M, mechanical stress; HMGB1, high mobility group box-1; MIF, macrophage migration inhibitory factor; IHC, immunohistochemistry; AST, aspartate aminotransferase; ALT, alanine transaminase.