Skip to main content
. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: Cancer Res. 2010 Dec 15;70(24):10464–10473. doi: 10.1158/0008-5472.CAN-10-0732

Figure 3. Reduced vasculogenesis and bone marrow macrophages in PISA/ErbB2 mammary tumors.

Figure 3

Analysis of mammary tumors in PISA mice (N=10), with or without Ponasterone A-induced IκBαSR expression to determine: A, Microvessel density; B, Histopathology by hematoxylin and eosin staining (left), immunostaining to demarcate CD31 (middle), CD34 (right) positive tumor blood vessels and C, immunohistochemical staining for candidate proangiogenic factors; E, Quantitation of immunohistochemical staining for proangiogenic factors, shown as mean + SEM (* P< 0.05, ** P<0.01). All pictures taken using 40x objective.