Table 1a. Frequency of ERG oncoprotein expression in whole-mount prostatectomy specimens.

ERG	Individual tumors	Benign glands
Positive	117	22
Negative	144	200 000
Specificity=99.99% Sensitivity=44.83% PPV 84.17% and NPV=99.93%

Sensitivity and specificity of the ERG oncoprotein nuclear staining distinguishing tumor foci from benign glands in 132 whole-mounted prostate sections (261 tumor foci and about 200,000 benign glands). Number of benign glands represents an estimate based on counting of the number of benign glands in three average size sections of this cohort (average 1550 benign glands/section) multiplied by 132 sections.