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. Author manuscript; available in PMC: 2010 Dec 28.
Published in final edited form as: Development. 2008 Oct 23;135(23):3871–3879. doi: 10.1242/dev.025767

Figure 7. Aberrant cell migration in the Wnt5a−/− palate.

Figure 7

(A-A″) Egfp-expressing mesenchymal cells from the anterior palate, when grafted to the anterior region of an explanted wild-type palatal shelf, exhibit a directional migration towards to the lateral side after 24 hours. Arrows indicate the migrating cells. (B-B″) Egfp-expressing mesenchymal cells from the posterior palate, when grafted to the posterior region of an explanted wild-type palatal shelf, show a directional migration towards the anterior end after 24 hours. (C-C″,D-D″) Directional migration by the Egfp-expressing cells is not observed when these cells are grafted to either the anterior (C-C″) or the posterior (D-D″) palatals shelves from Wnt5a mutants.