Figure 3.

The effect of tensile force $f_{ext}$ on the weighted average of αIIbβ3-fibrinogen bond lifetimes, t, shown on a semilogarithmic scale. The least-squares fit of the experimental data points for the αIIbβ3-fibrinogen bond lifetimes (black squares) with the theoretical dependence of the bond lifetimes on pulling force, $\langle t\left(f_{ext}\right)\rangle$(solid line), was used to estimate the kinetic parameters underlying the force-induced rupture of single bonds between the fibrinogen ligands and the αIIbβ3 receptors summarized in the main text.