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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Arch Ophthalmol. 2010 Nov;128(11):1462–1471. doi: 10.1001/archophthalmol.2010.261

Table 5.

Haplotype Analysis of the NHS and HPFS cohorts, blocks were defined by the method outlined by Gabriel et al. 2005

Block 2 rs7495128 rs2414687 Overall
Frequency,
Percent*
Frequency Among Cases,
Percent (Number of
Chromosomes)
Frequency Among
Controls, Percent
(Number of
Chromosomes)
Chi Square P-Value
h1 G G 0.517 0.568 (184) 0.499 (478) 4.55 0.0329
h2 G T 0.259 0.231 ( 75) 0.269 (258) 1.77 0.1833
h3 A G 0.224 0.201 ( 65) 0.232 (222) 1.341 0.2469
*

Overall frequency of each haplotype in the study population (percentages may not total exactly 100% due to rounding)

Frequency of each haplotype and the estimated number of chromosomes containing each haplotype among cases and controls, respectively. Percentages may not total exactly 100% due to rounding.

P-value testing the significance of each haplotype versus all others.