Fig. 6.

Migration inhibitory factor (MIF)/tetanus toxoid (TTX) DNA vaccine treatment inhibits increase in proinflammatory cytokines in colon of mice with dextran sulphate sodium (DSS)-induced colitis. Results are given as means ± standard error. Statistical significance was assessed compared with saline and DSS-treated mice. *P < 0·05, **P < 0·01; n = 4–5 in each group. Normal: non-treated mice. Saline: saline-treated mice given 3% DSS for 7 days. pCAGGS: pCAGGS-treated mice given 3% DSS for 7 days. MIF/TTX: MIF/TTX DNA vaccine-treated mice given 3% DSS for 7 days.