Table 3.
Costs and Costs per Disability-Adjusted Life Year (DALY) Averted by Routine Monitoring Tests
| Test | Events detected by routine tests | DALYs averted by routine tests | Cost of all routine tests | Cost of care averted by routine tests | Cost of all routine tests minus the cost of care averted | Cost per DALY averted by routine tests (95% CIa) |
|---|---|---|---|---|---|---|
| Tests conducted at baseline | ||||||
| SGOT/SGPT | 1 | 0.394 | $6552 | $477 | $6075 | $15,419 ($2769–$70,599) |
| Creatinine | 1 | 0.022 | $3198 | $53 | $3145 | $142,955 ($25,789–$670,519) |
| Glucose | 0 | 0 | $2631 | $0 | $2631 | No change (≥$5061) |
| CBC (hemoglobin, neutrophils, and platelets) | 25b | 5.344 | $7824 | $1509 | $6315 | $1182 ($802–$1810) |
| Hematocrit (spun)c | 25b | 5.344 | $430 | $1509 | −$1079 | Cost-saving |
| Tests conducted at follow-up | ||||||
| SGOT/SGPT | 0 | 0 | $27,600 | $0 | $27,600 | No change (≥$19,036) |
| Creatinine | 0 | 0 | $13,176 | $0 | $13,176 | No change (≥$170,455) |
| Glucose | 6 | 0.936 | $11,373 | $2158 | $9215 | $9845 ($4583–$25,970) |
| CBC (hemoglobin, neutrophils, and platelets) | 14d | 2.807 | $31,080 | $819 | $30,261 | $10,781 ($6459–$19,376) |
| Hematocrit (spun)c | 14d | 2.807 | $1709 | $819 | $890 | $317 ($190–$570) |
NOTE. All dollar amounts are in US dollars. CBC, complete blood count; CI, confidence interval; SGOT/SGPT, serum glutamic oxaloacetic transaminase/serum glutamic pyruvic transaminase.
The 95% CI represents the cost per DALY averted calculated for the upper and lower bounds of the 95% confidence interval for the number of events detected by a routine test.
Includes 11 cases of grade 3 anemia (0.090 DALYs averted per case detected) and 14 cases of grade 4 anemia (0.311 DALYs averted per case detected); neutropenia and thrombocytopenia were excluded from further analyses because no cases were detected through routine testing.
Assumes the same test performance as hemoglobin (CBC).
Includes 7 cases of grade 3 anemia and 7 cases of grade 4 anemia.