Table 1. Sensitivity and specificity for detection of TB in slides prepared from sputum samples from TB suspects.
ZN | Routine FM | iLED | Fraen AFTER | Lumin | |
Sensitivity in culture positive sputa (%; 95% CI) | 33/53 (62.3%; 47.9–75.2) | 29/53 (54.7%; 40.4–68.4) | 37/53 (69.8%; 55.7–81.7) | 38/53 (71.7%; 57.7–83.2) | 36/53 (67.9%; 53.7–80.1) |
Very low positive (scanty) | 2 | - | 6 | 6 | 7 |
Low positive (1+) | 8 | - | 9 | 10 | 8 |
High positive (2+, 3+) | 23 | - | 22 | 22 | 21 |
Specificity in culture negative sputa (%; 95% CI) | 125/127 (98.4%; 94.4–99.8) | 127/127 (100%; 97.1–100.0)* | 126/127 (99.2%; 95.7–100.0) | 121/127 (95.3%; 90.0–98.2) | 126/127 (99.2%; 95.7–100.0) |
*one-sided, 97.5% confidence interval.
A different grading scheme was used for routine FM and hence grading results were excluded from analysis.