Table I.
Composition of Scaffolds
| Scaffold code | Height of the scaffold (mm) | Concentration of the drug in loading solution (mg/mL) | Drug | Concentration of chitosan in coating solution (%, w/v) | Dissolution medium |
|---|---|---|---|---|---|
| SSS-1 | 3 | 25 | Gatifloxacin | – | PBS |
| SSS-2 | 6 | 25 | Gatifloxacin | – | PBS |
| SSS-3 | 12 | 25 | Gatifloxacin | – | PBS |
| SSS-4 | 12 | 12.5 | Gatifloxacin | – | PBS |
| SSS-5 | 12 | 6.25 | Gatifloxacin | – | PBS |
| SSS-6 | 12 | 25 | Fluconazole | – | PBS |
| SSS-7 | 12 | 25 | Gatifloxacin | 0.5 | PBS |
| SSS-8 | 12 | 25 | Gatifloxacin | 1.0 | PBS |
| SSS-9 | 12 | 25 | Gatifloxacin | – | SBF |
PBS phosphate-buffered saline, SBF simulated body fluid