Table I.

Dissolution Efficiency, Dissolution Percentage, and Dissolution Rate Values at 30 Min for Etodolac PM and Etodolac CE Systems at pH 1.2

Parameters	Inutec						HPβCD						Tromethamine
	1:1		1:2		1:5		1:1		1:2		1:5		1:1		1:2		1:5
	PM	CE	PM	CE	PM	CE	PM	CE	PM	CE	PM	CE	PM	CE	PM	CE	PM	CE
DP30	25.8	47	26.1	42	38	81	8	35	9	44	15	71	27	35	25	40	34	59
DE30	19.10	32.75	16.92	30.16	24.2	66.75	6.83	26.75	7.08	34.11	12.91	63.25	22.72	28.08	20.83	35.83	30.33	50.41
DR30 (μg/min)	430	783.33	435	700	633.33	1,350	133.3	583.33	150	733.33	250	1,183.3	450	583.33	416.67	666.67	566.66	983.33

Etodolac DP₃₀ = 3 μg/min, DE₃₀ = 2.41 μg/min, and DR₃₀ = 50 μg/min

DP ₃₀ dissolution percentage at 30 min, DE ₃₀ dissolution efficiency at 30 min, DR dissolution rate at 30 min, PM physical mixtures, CE coevaporated, HPβCD 2-hydroxypropyl-β-cyclodextrin