Table II.

Effect of Sumatriptan Formulations on Basal Reaction Time of Mice in Hot Plate Method

S. No.	Basal reaction time		Reaction time after drug administration (min)
	Paw licking (s, mean ± SD, n = 3)	Jump response (s, mean ± SD, n = 3)	Paw licking (s, mean ± SD, n = 3)				Jump response (s, mean ± SD, n = 3)
			15	30	60	120	15	30	60	120
1	7.51 ± 0.31		6.56 ± 0.56	6.83 ± 0.10	7.41 ± 0.61	7.66 ± 0.42
2		6.82 ± 0.42					6.15 ± 0.24	6.73 ± 0.41	6.88 ± 0.35	7.06 ± 0.36
3	5.61 ± 0.15		7.14 ± 0.42	5.42 ± 0.17	7.66 ± 0.22	7.22 ± 0.16
4	4.35 ± 1.17		5.57 ± 0.72	5.12 ± 0.37	6.86 ± 0.47	7.19 ± 1.36
5		7.54 ± 0.19					8.82 ± 0.56	9.76 ± 0.57	10.3 ± 0.41	10.8 ± 0.17
6	9.76 ± 0.37		8.91 ± 1.24	7.63 ± 0.55	10.82 ± 0.75	15a

SD standard deviation

^aA cut off- time of 15 s was taken as maximum antinociception response to avoid injury to the paws