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. 2010 Dec 3;11(4):1718–1725. doi: 10.1208/s12249-010-9540-7

Table III.

Effect of Sumatriptan Formulations on 0.6% Acetic Acid Induced Abdominal Writhing in Mice

S. No. Treatment Number of writhing (15 min)
1 Control (acetic acid) 43.45 ± 1.92
2 Solution of 1 mg/kg pure sumatriptan drug in phosphate buffer (pH 7.4) 39.83 ± 1.86
3 Organogel containing Sumatriptan 0.5 mg/kg + acetic acid 37.61 ± 2.47
4 Organogel containing Sumatriptan 1 mg/kg + acetic acid 34.77 ± 2.56
5 Organogel containing Sumatriptan 1.5 mg/kg + acetic acid 30.53 ± 2.33
6 Organogel containing Sumatriptan 2 mg/kg + acetic acid 28.68 ± 3.2