Table 1. Key High-Resolution Structures with Relevance for Neurobiologists: Channels, Transporters, and Receptors.

		Resolution^a	Reference
Ligand-gated ion channels: whole channels	Torpedo marmorata nicotinic acetylcholine receptor	4.0 Å	Miyazawa et al., 2003
Ligand-gated ion channels: extracellular domains	Mollusc AChBPs
	Limnea stagnalis AChBP	2.7 Å	Brejc et al., 2001
	Limnea stagnalis AChBP: conotoxin complex	2.4 Å	Celie et al., 2005a
	Limnea stagnalis AChBP: carbamoylcholine and nicotine complexes	2.2 Å	Celie et al., 2004
	Glutamate receptors: extracellular domains
	AMPA (GluR2)	1.9 Å	Armstrong et al., 1998
	AMPA (GluR2): agonist, antagonist, and modulator complexes	2.1 Å	Sun et al., 2002
	Kainate R (GluR5): antagonist complexes	1.74 Å	Mayer et al., 2006
	Kainate R (GluR6): agonist complexes	1.65 Å	Mayer, 2005a
	NMDAR (NR1/NR2A heteromer)	1.88 Å	Furukawa et al., 2005
Potassium channels: whole channels	Rat Kv1.2/Kvβ complex	2.9 Å	Long et al., 2005
	Archaeal voltage-gated channel KvAP	3.2 Å	Jiang et al., 2003
	Bacterial potassium channel: KcsA	2.0 Å	Zhou et al., 2001
	Bacterial potassium channel MthK	3.3 Å	Jiang et al., 2002
	Bacterial inward rectifier KirBac1.1	3.65 Å	Kuo et al., 2003
	Bacterial nonselective cation channel NaK	2.4 Å	Shi et al., 2006
Potassium channel intracellular domains and regulatory complexes	Kv4.3/KChIP1 complex	3.2 Å	Pioletti et al., 2006; Wang et al., 2007
	Kir3.1 intracellular domain	1.8 Å	Nishida and MacKinnon, 2002
	HERG PAS domain	2.6 Å	Morais Cabral et al., 1998
	SK channel intracellular domain: Ca²⁺/CaM complex	1.6 Å	Schumacher et al., 2001
Voltage-gated calcium channels: intracellular domains	Ca_Vβ and Ca_Vβ-AID complex	2.0 Å	Chen et al., 2004; Opatowsky et al., 2004; Van Petegem et al., 2004
Voltage-gated calcium channels: intracellular domains	Ca²⁺/CaM-Ca_V1.2 IQ domain complex	2.0 Å	Fallon et al., 2005; Van Petegem et al., 2005
Cyclic nucleotide gated channels	HCN2 Cyclic nucleotide binding domain/cAMP	2.0 Å	Zagotta et al., 2003
Cyclic nucleotide gated channels	HCN2 Cyclic nucleotide binding domain/cGMP	1.9 Å	Zagotta et al., 2003
TRP Channels	N-terminal Ankyrin repeat domain TRPV2	1.6 Å	Jin et al., 2006; McCleverty et al., 2006
TRP Channels	TRPM7 kinase domain	2.4 Å	Yamaguchi et al., 2001
Chloride channels: whole channel	Bacterial chloride channel	3.0 Å	Dutzler et al., 2002
Chloride channel intracellular domains	Human ClC-5 CBS domain (ATP and ADP)	2.3 Å	Meyer et al., 2007
Ca²⁺ ATPase	No nucleotide, with calcium	2.6 Å	Toyoshima et al., 2000
Ca²⁺ ATPase	Magnesium fluoride	2.3 Å	Toyoshima et al., 2004
G protein-coupled receptors	Rhodopsin	2.8 Å	Palczewski et al., 2000
G protein-coupled receptors: extracellular domains	mGluR1 ligand binding domain: apo and gluatmate complex	2.2 Å	Kunishima et al., 2000
G protein-coupled receptors: extracellular domains	mGluR1 ligand binding domain: antagonist complex	3.3 Å	Tsuchiya et al., 2002
Amino acid transporters	Archaeal glutamate transporter	3.5 Å	Yernool et al., 2004
Amino acid transporters	Archaeal asparate transporter	1.65 Å	Yamashita et al., 2005

Where multiple similar structures are solved, the highest resolution obtained is indicated.