Table 3.

Quantification of Tumorigenesis of Sorted Breast Cancer Metastatic Pleural Effusion Cells with or Without Adjunction of Feeder Populations

	Experiment 1 (positive sites/total sites)		Experiment 2 (positive sites/total sites)		Summary (%)
Feeder cells → Tumor cells ↓	10,000 ASC	10,000 irradiated CD90−CD31−CD45− tumor cells	10,000 ASC	10,000 irradiated CD90−CD31−CD45− tumor cells	10,000 ASC	10,000 irradiated CD90−CD31−CD45− tumor cells
100 high scatter CD90+CD31−CD45− tumor cells	9/20	0/20	8/20	0/20	42.5% p < 0.0005a	0%
100 low scatter CD90+CD31−CD45− tumor cells	3/20	5/20	1/20	1/20	10% N.S.a	15%
100 CD90−CD31−CD45− tumor cells	0/20	0/20	0/20	0/20	0% N.S.a	0%
Ø	0/20	0/20	ND	ND	0% N.S.a	0%

Experiment 1 utilized NOD-SCID mice; experiment 2 used IL2rγ-null mice. χ² comparison between ASC and irradiated tumor feeder cells.

IL, interleukin.

^ap-value by χ².