Table 1.
Parameter Combinations for the 10 Best-Fit Susceptible-Infected-Recovered Susceptible Simulations at the Arizona, Florida, Illinois, New York, and Washington State Sitesa,b
Ordered Model Rank | L, Years | D, Days | R0max, Persons/Person | R0min, Persons/Person |
1 | 5.35 | 3.24 | 3.52 | 1.12 |
2 | 5.40 | 2.41 | 2.89 | 1.16 |
3 | 3.28 | 4.18 | 3.40 | 1.22 |
4 | 3.70 | 2.03 | 2.05 | 1.15 |
5 | 7.77 | 2.59 | 3.69 | 1.30 |
6 | 6.23 | 2.37 | 2.71 | 1.23 |
7 | 6.05 | 2.56 | 3.79 | 1.06 |
8 | 4.61 | 2.71 | 2.61 | 1.29 |
9 | 7.39 | 2.85 | 3.69 | 1.27 |
10 | 3.58 | 3.61 | 3.19 | 1.20 |
Abbreviations: R0max, a constant that defines the maximum basic reproductive number, R0(t), at zero absolute humidity; R0min, a constant that defines a baseline level for basic reproduction number, R0(t), at high absolute humidity; RMS, root mean square; SIRS, susceptible-infected-recovered susceptible.
Adapted from Shaman et al. (2).
At each site, 5,000 simulations were performed with the parameters R0max, R0min, D (mean infection period), and L (mean duration of immunity) randomly chosen from within specified ranges. Best-fit SIRS simulations were selected for the 5 sites in aggregate based on RMS error after scaling the 31-year mean daily infection number to the 31-year mean observed daily excess pneumonia and influenza mortality rate at each site.