Table 2.
Associations of Estimated GFR categories with Advanced Heart Failure Symptoms in Logistic Regression Analyses
| Estimated GFR (ml/min/1.73m2) | ||||
|---|---|---|---|---|
| >50 | 40–50 | 30–40 | <30 | |
|
Creatinine | ||||
| Unadjusted OR | 1.0 (ref) | 1.18 (0.93–1.50) | 1.27 (1.00–1.63) | 2.10 (1.66–2.65) |
| Adjusted OR1 | 1.0 (ref) | 1.05 (0.80–1.38) | 1.03 (0.77–1.37) | 1.53 (1.14–2.05) |
| Adjusted OR2 | 1.0 (ref) | 1.09 (0.78– 1.51) | 1.08 (0.76– 1.53) | 1.37 (0.96–1.97) |
|
Cystatin C | ||||
| Unadjusted OR | 1.0 (ref) | 1.55 (1.23–1.95) | 2.08 (1.66–2.60) | 2.64 (2.05–3.40) |
| Adjusted OR | 1.0 (ref) | 1.38 (1.06–1.78) | 1.39 (1.09–1.82) | 2.15 (1.54–3.00) |
| Adjusted OR2 | 1.0 (ref) | 1.54 (1.13–2.11) | 1.56 (1.12–2.18) | 2.09 (1.38– 3.15) |
1
adjusted for sex, race, current smoking status, coronary artery disease, diabetes, asthma, peripheral vascular disease, hemoglobin, BMI and clinical site
2
excludes persons with history of asthma or current smoking