Table 4.
Characteristics independently associated with advanced heart failure-related symptoms among persons with CKD
| Unadjusted OR | Adjusted OR1 | Adjusted OR2 | |
|---|---|---|---|
| Female sex | 1.78(1.50– 2.11) | 1.45 (1.17–1.79) | 1.57 (1.21– 2.04) |
| Race | |||
| White | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) |
| Black | 2.20 (1.84–2.62) | 1.42 (1.15–1.76) | 1.61 (1.25–2.09) |
| Other | 1.22 (0.82–1.82) | 1.53 (0.97–2.43) | 1.82 (1.07– 3.11) |
| BMI | |||
| <27 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) |
| 27- <30 | 1.41 (1.05– 1.89) | 1.52 (1.10– 2.10) | 1.69 (1.10– 2.59) |
| 30- <35 | 1.78 (1.36– 2.32) | 1.78 (1.33– 2.38) | 2.44 (1.67– 3.55) |
| >35 | 4.61 (3.62– 5.88) | 3.99 (3.03– 5.27) | 5.56 (3.89– 7.96) |
| Current smoker | 2.05 (1.63– 2.59) | 2.25 (1.71– 2.95) | N/A |
| Asthma | 2.27 (1.81– 2.85) | 2.02 (1.55– 2.64) | N/A |
| Coronary Artery Disease | 1.92 (1.57– 2.35) | 1.77 (1.41– 2.23) | 1.84 (1.39– 2.43) |
| Diabetes | 2.11 (1.78– 2.51) | 1.35 (1.10– 1.66) | 1.36 (1.06– 1.75) |
| Peripheral Vascular Disease | 2.77 (2.05– 3.75) | 2.29 (1.61– 3.26) | 2.98 (1.96– 4.53) |
1
adjusted for sex, race, current smoking status, coronary artery disease, diabetes, asthma, peripheral vascular disease, hemoglobin, BMI and clinical site
2
excludes persons with history of asthma or current smoking