Skip to main content
. Author manuscript; available in PMC: 2011 Dec 10.
Published in final edited form as: Circ Res. 2010 Oct 14;107(12):1470–1482. doi: 10.1161/CIRCRESAHA.110.227371

Figure 8. FoxO1-induced autophagy is required to maintain cardiac function after starvation.

Figure 8

Cardiac function was evaluated in the Tg-FoxO1m, c-FoxO1−/−, beclin1+/− and control mice with echocardiographic analyses both at baseline and after 48 hours of starvation. A–B) Left ventricular ejection fraction (LVEF) and fractional shortening (%FS) in control, Tg-FoxO1m, c-FoxO1−/− mice. C–D) LVEF and FS in control and beclin1+/− mice. * p<0.05, **p<0.01. N=6 in each group.