Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Key Differences Between World Health Organization and Immune-Related Response Criteria
| WHO criteria | irRC | |
|---|---|---|
| New lesions | Always mean progressive disease | Incorporated into measurement of total tumor burden that determines response |
| Progressive disease | ≥25% increase in sum of products of diameters at any time | ≥25% increase in sum of products of diameters, confirmed by repeat scans at least 4 weeks later |
WHO, World Health Organization; irRC, immune-related response criteria.
