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. 2010 Dec;26(12):1307–1311. doi: 10.1089/aid.2010.0135

FIG. 4.

FIG. 4.

Fitness of CP and VC virus and viral constructs with sequences of relevant gag regions displayed below each experiment. (A) Fitness of recombinant pseudotyped NL43 constructs in a single cycle assay. Results depict duplicate or triplicate experiments in one donor. (B) Fitness of replication-competent virus from VC and CP as compared to Ba-L laboratory strain virus, as measured by p24 ELISA. Results depict triplicate experiments. (C) Fitness of CP and VC gag-NL43 constructs containing substitutions in residues 94 and/or 95. Results depict duplicate or triplicate experiments in three different donors. (D) Fitness of replication-competent recombinant gag-NL43 mutants. Results depict duplicate or triplicate experiments in three different donors. (Color image can be found at www.liebertonline.com/aid).