Table 3.
Endothelial function across oral contraceptive phases in group VLD and group LD
| Group VLD (n=11) |
p value | Group LD (n=11) |
p value | ||||
|---|---|---|---|---|---|---|---|
| Active | EE | Pill-free | Active | Pill-free | |||
| Baseline FMD diameter, mm | 3.15±0.14 | 3.19±0.12 | 3.21±0.11 | .560 | 3.16±0.13 | 3.18±0.13 | .193 |
| FMD, % change | 5.86±0.63 | 8.92±0.47* | 6.56±0.70 | .001 | 9.02±0.72 | 7.33±0.84 | .029 |
| TTP, s | 58±8 | 50±7 | 59±11 | .747 | 47±6 | 48±5 | .851 |
| Shear rate TTP AUC, velocity/diameter | 6275±479 | 6237±556 | 6761±652 | .533 | 6022±495 | 6604±544 | .151 |
| Normalized response, % FMD/shear rate TTP AUC | 0.0010±0.0017 | 0.0016±0.0002* | 0.0011±0.0002 | .006 | 0.0016±0.0001 | 0.0011±0.0001 | .030 |
| Baseline NTG diameter, mm | 3.14±0.13 | 3.21±0.13 | 3.21±0.12 | .219 | 3.13±0.13 | 3.17±0.13 | .115 |
| NTG, % change | 20.56±1.96 | 20.97±1.91 | 20.22±1.58 | .840 | 23.29±1.75 | 22.60±1.99 | .565 |
Values are means±SE.
Significantly different from active and pill-free phases.