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Overexpression of Pim-1 in human bladder cancer specimens. Pim-1 is overexpressed in both cytoplasm and nucleus of bladder cancer cells. Normal bladder epithelium cells show no or minimal staining (A&D). Bladder cancer cells show cytoplasm and nucleus positive staining (B&E). Invasive bladder cancer cells show strong staining(C&F). Magnification × 200 (A, B, C), or × 400 (D, E, F).
