Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Dec 29;5(12):e15115. doi: 10.1371/journal.pone.0015115

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Pyo et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

The progenitor haplotype contained the 2DL5-lineage III segment in the centromeric region. The diversification that resulted in the formation of the Cen-A and Cen-B lineages occurred ∼6 mya, contemporaneous with human:chimpanzee speciation. The Tel-A:Tel-B divergence is much younger occurring ∼1.7 mya conincident with the timing for the duplication of the 2DL5-lineage III progenitor that gave rise to 2DL5-2DS3 and 2DL5-2DS5. This duplication could have produced either a Cen-B:Tel-B or Cen-A:Tel-B haplotype. Subsequent recombinations have given rise to the haplotype structures present today.