Figure 13. Expression of fibrogenic activation and cellular proliferation-related genes in myofibroblasts isolated from the liver of control and MTA-treated Mdr2−/− mice.

Mdr2−/− mice were treated for three weeks with MTA or vehicle as described in the Methods section. At the end of the treatments hepatic myofibroblasts were isolated and the mRNA levels of the indicated genes were measured. Data are means ±SEM of three independent cell preparations per condition. *P<0.05 vs vehicle-treated Mdr2−/− mice.