Figure 2. A schematic representation of genome changes found in T. p. pallidum, T. p. pertenue strains and Fribourg-Blanc isolate.

A A schematic representation of indels found in all T. p. pertenue strains and the Fribourg-Blanc isolate but not found in any of the investigated T. p. pallidum strains (see also Table 3). Please note that TP0132 gene was not annotated in pertenue and Fribourg-Blanc strains. B Identified variable genomic regions in most of the investigated strains and isolates (see also Table 2). For more detailed structure of TP0126–TP0127 region see Figure 3, for details on TP0433–TP0434 locus, see [26]. C Indels specific for individual strains and isolates (see also Table 4). T. p. pallidum strains causing syphilis are shown in bold. Deletions are shown as vertical lines, insertions as lines with black triangles.