Table 3. Biomarker levels in Malawian children with uncomplicated malaria (UM), retinopathy confirmed cerebral malaria (CM-R) or non-malarial fever with altered consciousness (CNS).

	UM (n = 32)	CM-R (n = 38)	CNS (n = 24)
Ang-1, ng/mL	14 (4.2–132)**	3.1 (0.94–9.2)	10 (3.1–69)**
Ang-2, ng/mL	5.2 (2.0–41)	7.6 (3.1–34)	5.08 (1.67–14.29)*
Ang-2:Ang-1	0.39 (0.04–2.6)**	2.3 (0.75–6.6)	0.34 (0.03–2.5)**
sTie-2, ng/mL	48 (32–84)**	66(42–95)	67 (43–124)
VWFpp, nmol/L	32 (10–53)**	70 (13–1127)	23 (8.1–106)**
VWF, nmol/L	144 (23–301)**	357 (157–654)	169 (73–524)**
sICAM-1, ng/mL	660 (447–1761)**	1154 (718–2073)	1016 (675–4358)
VEGF, ng/mL	0.17 (0.02–9.1)*	0.55 (0.02–6.4)	0.46 (0.02–2.9)
IP-10, ng/mL	0.60 (0.05–8.3)	1.0 (0.13–8.1)	0.69 (0.02–2.6)

Median (range);

*p<0.05;

**p<0.01 for difference compared to CM-R (corrected for multiple testing at 18 pair-wise comparisons using Holm's test).