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. 2010 Oct 27;60(1):248–257. doi: 10.2337/db10-0104

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© 2011 by the American Diabetes Association.

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FIG. 5. — Age-dependent expression of proinflammatory cytokines by pancreatic islets. Pancreatic islets were purified from NOD.Lt mice (n = 5 per group) of the ages shown, and RNA was analyzed by Taqman PCR for relative expression of IL-1β, IL-6, TNF, and IFN-γ. *P < 0.05; ***P < 0.0001 (one-way ANOVA with post hoc analysis for linear trend).