FIG. 1.

Enterovirus (EV) RNA positivity in serum samples during different stages of the diabetic disease process. 6 month period prior AAb, 6-month time window before autoantibody seroconversion; Aab-T1D, period from autoantibody seroconversion to diagnosis of type 1 diabetes; birth-before 6 month period prior Aab, time from birth to 6 months before the seroconversion to positivity for the first autoantibody; birth-T1D, time from birth to diagnosis of type 1 diabetes. A: the whole cohort. B: boys. C: girls. ■, case children; □, control children. The differences between case and control children were tested using conditional logistic regression analysis (P values shown).