TABLE 3.
Hazard ratios of type 2 diabetes according to updated 4-year changes in initial and current drinking category (n = 38,031)
| Initial alcohol drinking category (g/day) | Alcohol drinking category 4 years later (g/day) |
Ptrend* | ||
|---|---|---|---|---|
| Light (0–4.9) | Moderate (5.0–29.9) | Heavier (≥30.0) | ||
| Light (0–4.9) | ||||
| Multivariable-adjusted† | 1.00 [Reference] | 0.75 (0.62–0.90) | 0.35 (0.11–1.10) | <0.001 |
| Person-years | 169,623 | 31,723 | 1,127 | |
| Number of cases | 875 | 125 | 3 | |
| Moderate (5.0–29.9) | ||||
| Multivariable-adjusted† | 1.09 (0.92–1.30) | 0.74 (0.65–0.83) | 0.59 (0.45–0.77) | <0.001 |
| Person-years | 27,841 | 134,942 | 16,050 | |
| Number of cases | 159 | 496 | 60 | |
| Heavier (≥30.0) | ||||
| Multivariable-adjusted† | 0.78 (0.44–1.38) | 0.67 (0.52–0.88) | 0.50 (0.40–0.63) | 0.08 |
| Person-years | 2,089 | 15,036 | 30,067 | |
| Number of cases | 12 | 65 | 110 | |
*Ptrend values were derived from tests of linear trend across increasing categories of alcohol use by treating the median value of each category as a continuous variable.
†Hazard ratios (95% CIs) were calculated using Cox proportional hazards model and adjusted for the covariates listed in Table 2.