TABLE 4.
Associations of a 7.5 g/day increment in alcohol consumption from 1990–1994 on subsequent total adiponectin and hemoglobin A1c levels, classified by alcohol consumption in 1990
| Alcohol consumption in 1990 (g/day) | Mean increment in glycemic marker per 7.5 g/day increase in alcohol consumption from 1990–1994 |
|
|---|---|---|
| Total adiponectin (μg/ml) | HbA1c (%) | |
| Non (0) | ||
| Mean increment* | 1.2 ± 0.3 | −0.04 ± 0.02 |
| Number of participants | 151 | 267 |
| <1 drink/day (0.1–14.9) | ||
| Mean increment* | 0.5 ± 0.3 | −0.02 ± 0.02 |
| Number of participants | 355 | 610 |
| ≥1 drink/day (≥15.0) | ||
| Mean increment* | −0.6 ± 0.3 | 0.01 ± 0.01 |
| Number of participants | 191 | 311 |
| Pinteraction† | 0.002 | 0.02 |
*Values are mean increments (± SEM) per 7.5 g/day increment in alcohol consumption over 4 years and were calculated with a mixed ANOVA model that included terms for age, BMI, physical activity, smoking status, family history of type 2 diabetes, hypertension, hypercholesterolemia, cardiovascular disease, dietary glycemic load, fiber intake, trans fat intake, ratio of polyunsaturated fat and saturated fat (all energy-adjusted), coffee intake, total energy intake, and case-control status.
†Pinteraction value was derived by adding an interaction term between the 7.5 g/day increment of alcohol consumption (continuous), and initial alcohol consumption in 1990 (categorical) in the mixed ANOVA model.