Table 2.
Doses of opioids and traditional sedatives
| Medication | Artificial hydration | No artificial hydration | ||
|---|---|---|---|---|
| Opioid (OME) mg /24 h | At 48 h before death (N=107) | *At 24 h before death (N=111) | At 48 h before death (N=77) | *At 24 h before death (N=78) |
| Mean (95% CI) | 113.3 (73.8-152.9) | 102.2 (70.7-133.6) | 97.8 (56.7-138.9) | 96.9 (55.3-138.5) |
| Median | 60 | 60 | 36 | 36 |
| Range | 1-1560 | 1-1440 | 3-1000 | 1-1000 |
| BZD1 (PME) mg /24 h | At 48 h before death (N=18) | †At 24 h before death (N=24) | At 48 h before death (N=12) | †At 24 h before death (N=13) |
| Mean (95% CI) | 6.6 (4.1-9.1) | 7.9 (5.1-10.6) | 7.8 (4.9-10.6) | 7.4 (4.6-10.2) |
| Median | 5 | 5 | 6.2 | 7.5 |
| Range | 1-15 | 1-24 | 3-15 | 1-15 |
| Haloperidol (mg)/24 h | At 48 h before death (N=15) | ‡At 24 h before death (N=13) | At 48 h before death (N=14) | ‡At 24 h before death (N=13) |
| Mean (95% CI) | 4.01 (1.7-6.2) | 4.6 (2.3-6.9) | 4.4 (1.8-7.1) | 4.2 (1.3-7.1) |
| Median | 2.75 | 5 | 4 | 3 |
| Range | 1-15 | 1-15 | 1-19 | 1-19 |
*
The differences were not statistically significant, (Mann-Whitney U Test, P = 0.1);
†
The differences were not statistically significant, (Mann-Whitney U Test, P = 0.9)
1
Benzodiazepine;
‡
The differences were not statistically significant, (Mann-Whitney U Test, P = 0.5)