Representative graphs show apo B mRNA levels in FL83B cells treated with different concentrations of lipids (A, Dotap_chol; B, Dmtap_chol; C, Transfast_chol) and corresponding cell viability after 24 hours of siRNA-lipid treatments (D, Dotap_chol; E, Dmtap_chol; F, Transfast_chol). Apo B mRNA levels are expressed as a % of control transfection. Each value was derived from the mean ± SEM of duplicate cultures and is representative of at least two separate experiments. Cell toxicity levels are expressed as a % of control transfection. Each value was derived from the mean ± SEM of duplicate cultures and is representative of at least two separate experiments.