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. Author manuscript; available in PMC: 2010 Dec 30.
Published in final edited form as: Bioconjug Chem. 2010 Sep 15;21(9):1581–1587. doi: 10.1021/bc900482r

Figure 2. In vitro silencing of apo B by RNAi delivered by cholesterol modified lipids.

Figure 2

Representative graphs show apo B mRNA levels in FL83B cells treated with different concentrations of lipids (A, Dotap_chol; B, Dmtap_chol; C, Transfast_chol) and corresponding cell viability after 24 hours of siRNA-lipid treatments (D, Dotap_chol; E, Dmtap_chol; F, Transfast_chol). Apo B mRNA levels are expressed as a % of control transfection. Each value was derived from the mean ± SEM of duplicate cultures and is representative of at least two separate experiments. Cell toxicity levels are expressed as a % of control transfection. Each value was derived from the mean ± SEM of duplicate cultures and is representative of at least two separate experiments.