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. Author manuscript; available in PMC: 2010 Dec 30.
Published in final edited form as: Methods Enzymol. 2010;478:343–363. doi: 10.1016/S0076-6879(10)78017-4

Figure 3. High-affinity PAA probe binding to siglec-expressing cells shows the importance of intrinsic affinity in overcoming cis ligands.

Figure 3

A human BJAB B cell line (A) or murine B cells (B) were probed with native (NeuAc(Gc)α2,6-LacNAc-) or high-affinity BPC(BPA)NeuAc(Gc)α2,6-LacNAc- ligands appended to PAA. Reproduced with permission.