Table 2.
Comparison of antimicrobial consumption (defined daily doses/1000 inhabitants/day) in Osijek-Baranja county, as well as from Croatia and some European countries*
| Classes of antibiotics |
Osijek Baranja county |
Croatia |
Hungary |
Slovenia |
Czech Republic |
Austria |
Italy |
France |
Netherlands |
UK |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Total outpatient use |
17.57 |
23.50 |
19.63 |
17.10 |
16.65 |
12.49 |
25.63 |
28.97 |
9.78 |
14.90 |
| Penicillins total |
8.93 |
12.36 |
9.33 |
10.14 |
6.89 |
5.14 |
12.35 |
14.00 |
3.86 |
6.88 |
| Narrow spectrum |
1.24 |
1.60 |
1.34 |
2.61 |
2.24 |
1.15 |
0.01 |
0.16 |
0.44 |
0.66 |
| Broad spectrum |
4.00 |
4.84 |
3.31 |
3.23 |
2.59 |
1.07 |
6.54 |
7.92 |
1.77 |
4.47 |
| Penicillins combined |
3.69 |
5.86 |
4.67 |
4.14 |
1.96 |
2.91 |
5.78 |
5.46 |
1.39 |
0.89 |
| Cephalosporins total |
2.87 |
3.89 |
2.32 |
0.71 |
0.99 |
1.63 |
3.37 |
3.34 |
0.06 |
0.76 |
| Cephalosporins 1st generation† |
1.46 |
2.08 |
0.14 |
0.09 |
0.24 |
0.31 |
0.17 |
0.38 |
0.01 |
0.56 |
| Cephalosporins 2nd generation‡ |
1.01 |
1.36 |
1.73 |
0.54 |
0.75 |
0.46 |
1.23 |
1.31 |
0.03 |
0.19 |
| Cephalosporins 3rd generation§ |
0.40 |
0.44 |
0.45 |
0.09 |
0.00 |
0.86 |
1.94 |
1.65 |
0.01 |
0.01 |
| Macrolides, linkosamin |
1.13 |
2.10 |
3.14 |
3.18 |
2.49 |
2.89 |
5.01 |
4.85 |
1.33 |
2.31 |
| Short acting |
0.09 |
0.13 |
0.20 |
0.30 |
0.16 |
0.07 |
0.56 |
0.11 |
0.10 |
1.81 |
| Intermediate acting |
0.18 |
0.26 |
1.96 |
1.41 |
1.73 |
2.14 |
3.18 |
1.28 |
0.84 |
0.44 |
| Long acting |
1.04 |
1.50 |
0.34 |
1.29 |
0.50 |
0.46 |
1.19 |
0.79 |
0.33 |
0.04 |
| Tetracyclines total║ |
0.68 |
1.89 |
1.99 |
0.72 |
2.85 |
1.08 |
0.50 |
3.35 |
2.23 |
3.23 |
| Sulfonamides¶ | 1.72 | 1.71 | 1.27 | 1.16 | 1.18 | 0.40 | 0.70 | 0.45 | 0.67 | 1.05 |
*Data from ESAC project, 2003 (6).
†In Osijek-Baranja county, only cephalexin, because of minimal use of cefadroxil.
‡In Osijek-Baranja county, only cefuroxime.
§In Osijek-Baranja county, only ceftibuten.
║In Osijek-Baranja county, only doxycycline.
¶All, including combination with trimethoprime. In Osijek-Baranja county, sulfamethoxazole-trimethoprime.