Table 3.
Effect of rimonabant and indomethacin on the oedematous response in croton oil-induced ear dermatitis after 6 h and 24 h
| 6 h | 24 h | |||||
|---|---|---|---|---|---|---|
| Substance | Number of mice | Dose (µmol cm2-1) | Oedema (mg) mean ± SD | % reduction | Oedema (mg) mean ± SD | % reduction |
| Controls | 10 | – | 7.0 ± 0.8 | – | 2.3 ± 0.6 | – |
| Rimonabant | 10 | 0.3 | 3.0 ± 0.6** | 57 | 1.2 ± 0.4* | 48 |
| Indomethacin | 10 | 0.3 | 2.7 ± 0.9** | 61 | 2.2 ± 0.6 | 4 |
P < 0.005,
P < 0.001, significantly different from control values; one-way anova.