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Effects of peroxisome proliferator-activated receptor (PPAR) agonists on the expression of Bcl-2 or Bax. Cells were treated with gemfibrozil (10 µM), GW0742 (0.1 µM), pioglitazone (1 µM) or rosiglitazone (0.1 µM) following Protocol 3 and exposed to serum deprivation (SD; 48 h). (A) Bcl-2 and Bax expression was determined by Western blot analysis. Results are expressed as mean ± SEmean of four experiments run in triplicate. **P < 0.01 versus vehicle alone; °P < 0.01 versus basal.
