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. 2011 Jan;162(1):111–125. doi: 10.1111/j.1476-5381.2010.01032.x

Table 1.

EC50 values (M) of the selective PPAR agonists

Decrease of apoptosis Decrease of cell loss Decrease of caspase 3 activation
Agonist Single treatment Repeated treatment Single treatment Repeated treatment Single treatment Repeated treatment
Gemfibrozil 3.6 ± 0.5 × 10−6 7.4 ± 0.1 × 10−8 3.5 ± 0.2 × 10−6 5.7 ± 1.2 × 10−8 4.4 ± 0.4 × 10−6 6.3 ± 0.7 × 10−8
GW0742 1.1 ± 0.2 × 10−8 9.5 ± 1.4 × 10−10 7.5 ± 0.6 × 10−9 4.1 ± 0.8 × 10−10 1.6 ± 0.2 × 10−8 6.9 ± 0.1 × 10−10
Pioglitazone 2.4 ± 0.4 × 10−7 8.6 ± 1.0 × 10−9 3.0 ± 0.2 × 10−7 4.2 ± 0.4 × 10−9 1.9 ± 0.1 × 10−7 6.1 ± 0.1 × 10−9
Rosiglitazone 5.6 ± 1.2 × 10−8 1.7 ± 0.1 × 10−9 7.5 ± 0.7 × 10−8 1.1 ± 0.1 × 10−9 7.7 ± 0.8 × 10−8 2.7 ± 0.2 × 10−9