Table 1.

EC₅₀ values (M) of the selective PPAR agonists

	Decrease of apoptosis		Decrease of cell loss		Decrease of caspase 3 activation
Agonist	Single treatment	Repeated treatment	Single treatment	Repeated treatment	Single treatment	Repeated treatment
Gemfibrozil	3.6 ± 0.5 × 10−6	7.4 ± 0.1 × 10−8	3.5 ± 0.2 × 10−6	5.7 ± 1.2 × 10−8	4.4 ± 0.4 × 10−6	6.3 ± 0.7 × 10−8
GW0742	1.1 ± 0.2 × 10−8	9.5 ± 1.4 × 10−10	7.5 ± 0.6 × 10−9	4.1 ± 0.8 × 10−10	1.6 ± 0.2 × 10−8	6.9 ± 0.1 × 10−10
Pioglitazone	2.4 ± 0.4 × 10−7	8.6 ± 1.0 × 10−9	3.0 ± 0.2 × 10−7	4.2 ± 0.4 × 10−9	1.9 ± 0.1 × 10−7	6.1 ± 0.1 × 10−9
Rosiglitazone	5.6 ± 1.2 × 10−8	1.7 ± 0.1 × 10−9	7.5 ± 0.7 × 10−8	1.1 ± 0.1 × 10−9	7.7 ± 0.8 × 10−8	2.7 ± 0.2 × 10−9