Figure 4.
Effect of preincubation with 0.5 µmol·L−1 CGRP 8-37 on the vasoconstrictor response induced by electric field stimulation (EFS) in mesenteric segments from control (A), high-fat diet (HFD) (B) and HFD + rosuvastatin (C) rats. Results (mean ± SEM) are expressed as a percentage of previous contraction elicited by KCl. n= 6–10 animals per group. (D) Vasodilator response to exogenous CGRP in segments from control, HFD and HFD + rosuvastatin rats. Results (mean ± SEM) are expressed as a percentage of previous contraction elicited by noradrenaline. n= 6–10 animals per group.