Fig. 1.

μs-ms dynamics are significantly increased for the N-terminal β-strands of VDAC1. (A) Enlarged spectral regions and one-dimensional traces of a ¹H,¹⁵N-TROSY spectrum of hVDAC1 measured at a ¹H frequency of 900 MHz showing examples of broadened and nonbroadened peaks. (B) Chemical exchange rates (R_ex) measured at 900 MHz. The topology of VDAC1 is indicated at the top, with secondary structure elements highlighted in gray. Residues that could not be assigned are highlighted in red; E73 is indicated by a blue diamond.