Table 3.
Multivariate analysis for prognostic value of multidrug resistance related protein-1 G-1666A polymorphism in patients with hepatocellular carcinoma
| Genotypes |
DFS1 |
OS2 |
||
| HR (95% CI) | Pa | HR (95% CI) | Pa | |
| All (n = 162) | ||||
| AA+AG | 1 | |||
| GG | 3.067 (1.587-5.952) | 0.001 | ||
| Men (n = 147) | ||||
| AA + AG | 1 | 1 | ||
| GG | 3.154 (1.604-6.201) | 0.001 | 3.342 (1.474-7.576) | 0.004 |
a
Hazard ratio (HR) and P values were calculated using multivariate Cox regression. P < 0.05 was considered to indicate statistical significance;
1
Multivariate analysis of disease-free survival (DFS) in all patients was adjusted for sex, γ-glutamyl transpeptidase (GGT), α-fetoprotein (AFP), tumor size, ascites, and TNM stage; in male patients, it was adjusted for GGT, tumor size, and TNM stage;
2
Multivariate analysis of OS in male patients was adjusted for GGT, tumor size, ascites, cirrhosis, and TNM stage. OS: Overall survival; CI: Confidence interval.