Table 4.

Frequency of thrombophilic disorders in children and adolescents with portal vein thrombosis n (%)

Study	Coagulation inhibitor protein deficit		Gene mutations
	PC	PS	FVL	PTHR	MTHFR
Dubuisson et al[13] (n = 20)	9 (45)	13 (65)	NP	NP	NP
Uttenreuther-Fischer et al[2] (n = 23)	NP	NP	2 (9)	NP	NP
Heller et al[1] (n = 24)	NP	NP	4 (17)	0	1 (4)
Pinto et al[12] (n = 14)	6 (43)	3 (21)	0	1 (7)	3 (21)
Current study (n = 31)	4 (13)	4 (13)	2 (6.5)	3 (9.7)	16 (67.7)

PC: Protein C; PS: Protein S; FVL: Factor V Leiden; PTHR: Prothrombin; MTHFR: Methylenetetrahydrofolate reductase; NP: Not provided.