Table 2. Allele frequencies of the SNPs rs2066843 and rs2076756 in patients with Crohn's disease, ulcerative colitis and controls.
| Gene marker | Minor allele | Crohn's diseasen = 812 | Ulcerative colitisn = 442 | Controlsn = 1446 | ||||
| MAF | p value | OR [95% CI] | MAF | p value | OR [95% CI] | MAF | ||
| rs2066843 | T | 0.390 | 3.01×10−5 | 1.48 [1.23–1.78] | 0.300 | 9.67×10−1 | 1.01 [0.85–1.19] | 0.299 |
| rs2076756 | G | 0.380 | 4.01×10−6 | 1.54 [1.28–1.86] | 0.270 | 3.74×10−1 | 1.09 [0.94–1.27] | 0.286 |
| rs2066844 p.Arg702Trp | T | 0.089 | 1.43×10−6 | 2.07 [1.53–2.79] | 0.046 | 7.49×10−1 | 0.92 [0.60–1.40] | 0.050 |
| rs2066845 p.Gly908Arg | G | 0.042 | 1.1×10−2 | 1.72 [1.14–2.60] | 0.022 | 1.00 | 0.94 [0.51–1.73] | 0.024 |
| rs2066847 p.Leu1007fsX1008 | insC | 0.121 | 1.88×10−14 | 5.03 [3.54–7.15] | 0.022 | 3.91×10−1 | 0.76 [0.42–1.37] | 0.028 |
Minor allele frequencies (MAF), allelic test P-values, and odds ratios (OR, shown for the minor allele) with 95% confidence intervals (CI) are depicted for both the CD and UC case-control cohorts.